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Restrictions on the Horizon for Imports of Three Synthetic Opioids, One Synthetic Cannabinoid

The Drug Enforcement Administration has announced its intent to issue separate orders temporarily including the following substances into schedule I of the Controlled Substances Act: (1) the synthetic opioids N-(2-fluorophenyl)-N-(1-phenethylpiperidin-4-yl)propionamide (ortho-fluorofentanyl or 2-fluorofentanyl), N-(1-phenethylpiperidin-4-yl)-phenyltetrahydrofuran-2-carboxamide (tetrahydrofuranyl fentanyl) and 2-methoxy-N-(1-phenethylpiperidin-4-yl)-N-phenylacetamide (methoxyacetyl fentanyl); and (2) the synthetic cannabinoid methyl 2-(1-(4-fluorobenzyl)-1H-indazole-3-carboxamido)-3-methylbutanoate. Available information indicates that these substances have a high potential for abuse, no currently accepted medical use in treatment in the United States, and a lack of accepted safety for use under medical supervision.

The temporary scheduling orders will impose the administrative, civil and criminal sanctions and regulatory controls applicable to schedule I substances under the CSA on the manufacture, distribution, reverse distribution, possession, importation, exportation, research and conduct of instructional activities, and chemical analysis of these substances. They will be effective on the date they are published in the Federal Register, which will be no sooner than 11-12 October, and will remain in effect for two years, with a possible extension of one year.

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